Alice was raped by her boss when she was young and impressionable. Sonja is being physically abused by her older husband on a pretty consistent basis and close to the very end it is revealed that Sonja's husband is Zoe's father. And he has "volunteered" his services as a psychiatrist at Zoe's high school. Kate struggles with infertility and the friendship she developed with Zoe helps them both. Sadly, Alice's cancer turns terminal and she chooses Kate to parent Zoe after her death.
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